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Sunday 30 December 2012

Crabsallover Lipid & Cholesterol levels

Crabsallover tests: 
November 2006 / 25 November 2008 / 15 July 2010 / 26 January 2011 / 3 November 2011

Crabsallover Serum cholesterol: 
5.1mmol/L, 4.7mmol/L / 5.6mmol/L / 3.5mmol/L / 6.1mmol/L
Conclusion: trend is negative, aim to decrease serum cholesterol by 30% from 5.6 to <3.9mmol/L (target me 26 January 2011) but increased to 6.1mmol/L 3 November 2011

Crabsallover Serum triglycerides: 
Not tested 2.2 mmol/L / 1.5mmol/L (range: 0.5-2.3) / 1.0mmol/L / 2.0mmol/L
Conclusion: trend is positive but aim to decrease triglycerides 26% from 1.5 to <1.1mmol/L


Crabsallover Serum  HDL cholesterol: 
Not tested / 1.18 mmol/L / 1.35mmol/L ./ 1.09mmol/L / 1.4mmol/L
Conclusion: trend is positive but aim to increase HDL 15% from 1.35 to >1.55 mmol/L (@ 15 July 2010)

Crabsallover Serum LDL cholesterol: 
Not tested 2.5 mmol/L / 3.6mmol/L / 2.00mmol/L / 3.8mmol/L
Conclusion: trend is negative for LDL cholesterol, 3.6-3.8mmol/L are borderline high levels - aim for 50% decrease to <1.8mmol/L ie reduce by ~ 2mmol/L @ 3 November 2011

Crabsallover Serum cholesterol/HDL ratio: 
Not tested / 4.0 / 4.1 / 3.2 / 4.4
Conclusion: Lower serum cholesterol/HDL ratio by 27% from 4.1 to 3 - reduce total cholesterol and/or increase HDL @ 15 July 2010.


Overall Lipid & Cholesterol Conclusions: 
Reduce serum cholesterol, triglycerides and LDL cholesterol levels by 30%, 26% and 50% respectively. Increase HDL cholesterol levels by 15% @ 15 July 2010




Tactics
HeartUK pdf (accessed 30 December 2012)
  • Analyse & reduce / change fats eaten
    • reduce total amount of fat eaten
      • grilled chicken breast without skin contains third less saturated fat than with skin
    • reduce saturated fats (increases LDL cholesterol & risk of narrowed arteries)
      • butter, hard cheese, fatty meat, cream, lard, suet, ghee, coconut oil and palm oil.
    • replace saturated fats with unsaturated fats (lowers LDL & serum cholesterol) 
      • polyunsaturated fats (lowers serum cholesterol & blood triglycerides)
        • Oily fish provides polyunsaturated omega-3 fats 
          • 1.2g omega-3 fats / 100g pilchards
          • omega-3 fats reduces: carotid artery thickness, triglyercides, coronary incidents; increases HDL & reduces LDL cholesterol
      • monounsaturated fats (lowers LDL cholesterol whilst maintaining HDL cholesterol)
        • olive / rapeseed / corn oils
        • nuts and seeds
        • some margarines and spreads
        • cheeses low in fat & saturated fat: cottage cheese, ricotta & half-fat cheddar. 
  • consider Statins if diet modification does not work in a year
Serum Cholesterol

HeartUK
Guidelines for cholesterol levels have been set for healthy people and for those at high risk. High risk means someone with existing heart disease, high blood pressure, diabetes or with a family history of early heart disease. 
Recommendations for Healthy Adults Total cholesterol 5 mmol/l or less
Recommendations for High Risk Adults 4 mmol/l or less
http://www.heartuk.org.uk/index.php?/healthy_living/cholesterol_made_simple/

NHS
The government recommends that cholesterol levels should be less than 5mmol/L.
In the UK, two out of three adults have a total cholesterol level of 5mmol/L or above. On average, men in England have a cholesterol level of 5.5mmol/L and women have a level of 5.6mmol/L. The UK population has one of the highest average cholesterol concentrations in the world.
http://www.nhs.uk/Conditions/Cholesterol/Pages/Introduction.aspx

To convert mg/dl of HDL or LDL cholesterol to mmol/l, divide by 39.
http://www.faqs.org/faqs/diabetes/faq/part1/section-9.html

labtestsonline.org.uk
If you are taking treatment to lower your cholesterol, the target is to lower your total cholesterol to <4 mmol/L (156mg/dl), with a fall of around 20-25%.
http://www.labtestsonline.org.uk/understanding/analytes/cholesterol/test.html#what

www.heart.org
Less than 200 mg/dL = 5.1mmol/L = Desirable level that puts you at lower risk for coronary heart disease. A cholesterol level of 200 mg/dL or higher raises your risk.
200 = 5.1mmol/L to 239 mg/dL = 6.1 mmol/L = Borderline high
240 mg/dL = 6.1mmol/L and above High blood cholesterol. A person with this level has more than twice the risk of coronary heart disease as someone whose cholesterol is below 200 mg/dL.
http://www.heart.org/HEARTORG/Conditions/Cholesterol/AboutCholesterol/What-Your-Cholesterol-Levels-Mean_UCM_305562_Article.jsp

Serum Triglycerides
crabsallover History: http://crabsalloverhealth.blogspot.com/2010/06/crabsallover-lipid-cholesterol-levels.html

high triglyceride level combined with low HDL cholesterol or high LDL cholesterol seems to speed up atherosclerosis (the buildup of fatty deposits in artery walls). Atherosclerosis increases the risk for heart attack and stroke.
1.5mmol/L x 89 = 133.5 mg/dL
To convert mmol/l of triglycerides to mg/dl, multiply by 89.
http://www.faqs.org/faqs/diabetes/faq/part1/section-9.html
www.heart.org
Less than 150 mg/dL = 1.68mmol/L =Normal
150–199 mg/dL Borderline high =A triglyceride level of 150 mg/dL or higher is one of the risk factors of metabolic syndrome. Metabolic syndrome increases the risk for heart disease and other disorders, including diabetes.
200–499 mg/dL High
500 mg/dL and above Very high
The mean level of triglycerides for American adults age 20 and older is 144.2 mg/dl (1.6mmol/L)
http://www.heart.org/HEARTORG/Conditions/Cholesterol/AboutCholesterol/What-Your-Cholesterol-Levels-Mean_UCM_305562_Article.jsp

No figures cited: 
http://www.labtestsonline.org.uk/understanding/analytes/triglycerides/test.html#what

Serum HDL cholesterol

HeartUK
Guidelines for cholesterol levels have been set for healthy people and for those at high risk. 
Recommendations for Healthy Adults HDL cholesterol: Men – above 1.0 mmol/l
http://www.heartuk.org.uk/index.php?/healthy_living/cholesterol_made_simple/

Labtestsonline.org.uk: High levels of HDL cholesterol are better than low HDL cholesterol.  The higher your HDL cholesterol level, the lower risk of developing heart disease. There are two ways that HDL cholesterol values are interpreted—as a percent of total cholesterol or as a measured value.  Measured Value: If HDL cholesterol is less than 1.0 mmol/L in men there is an increased risk of heart disease. A desirable level of HDL is greater than 1.0 mmol/L for men and is associated with average risk of heart disease. A good level of HDL is 1.5 mmol/L or more and is associated with a less than average risk of heart disease.
http://www.labtestsonline.org.uk/understanding/analytes/hdl/test.html#what

To convert mg/dl of HDL or LDL cholesterol to mmol/l, divide by 39.
http://www.faqs.org/faqs/diabetes/faq/part1/section-9.html
www.heart.org
HDL Cholesterol Level Category
Less than 40 mg/dL (for men) = Low HDL cholesterol. A major risk factor for heart disease.
60 mg/dL and above = High HDL cholesterol. An HDL of 60 mg/dL and above is considered protective against heart disease.

With HDL (good) cholesterol, higher levels are better. Low HDL cholesterol (less than 40 mg/dL for men, less than 50 mg/dL for women) puts you at higher risk for heart disease. In the average man, HDL cholesterol levels range from 40 to 50 mg/dL. In the average woman, they range from 50 to 60 mg/dL. An HDL cholesterol of 60 mg/dL or higher gives some protection against heart disease. The mean level of HDL cholesterol for American adults age 20 and older is 54.3 mg/dL.
Smoking, being overweight and being sedentary can all result in lower HDL cholesterol. To raise your HDL level, avoid tobacco smoke, maintain a healthy weight and get at least 30-60 minutes of physical activity more days than not.
People with high blood triglycerides usually also have lower HDL cholesterol and a higher risk of heart attack and stroke. Progesterone, anabolic steroids and male sex hormones (testosterone) also lower HDL cholesterol levels. Female sex hormones raise HDL cholesterol levels.
http://www.heart.org/HEARTORG/Conditions/Cholesterol/AboutCholesterol/What-Your-Cholesterol-Levels-Mean_UCM_305562_Article.jsp

Serum LDL Cholesterol
HeartUK
Guidelines for cholesterol levels have been set for healthy people and for those at high risk. 
High risk means someone with existing heart disease, high blood pressure, diabetes or with a family history of early heart disease.
Recommendations for Healthy Adults LDL cholesterol  3 mmol/l or less
Recommendations for High Risk Adults LDL cholesterol: 2 mmol/l or less
http://www.heartuk.org.uk/index.php?/healthy_living/cholesterol_made_simple/

labtestsonline.org.uk: Elevated levels of LDL indicate risk for heart disease. Treatment (with diet or drugs) for high LDL aims to lower LDL to a target value of less than 3 mmol/L.
This is especially important if you have other risk factors for heart disease. Risk factors include cigarette smoking, hypertension, low HDL (< 1 mmol/L), family history, age (male 55 or older; female 65 or older), being overweight, and failure to exercise regularly.
http://www.labtestsonline.org.uk/understanding/analytes/ldl/test.html#what

“Bad” LDL cholesterol is seen as being worryingly high at 7 mmol/l, more healthy: 4.4mmol/l.  Optiimal: 1 to 3 mmol/L
http://crabsalloverhealth.blogspot.com/2010/11/benefits-of-high-doses-of-statins.html

UK Government advises  LDL should be <3mmol/L
http://www.nhs.uk/Planners/NHSHealthCheck/Pages/Healthycholesterol.aspx

To convert mg/dl of HDL or LDL cholesterol to mmol/l, divide by 39.
http://www.faqs.org/faqs/diabetes/faq/part1/section-9.html

Serum Total Cholesterol to HDL ratio
Labtestsonline.org.uk: High levels of HDL cholesterol are better than low HDL cholesterol.  The higher your HDL cholesterol level, the lower risk of developing heart disease. There are two ways that HDL cholesterol values are interpreted—as a percent of total cholesterol or as a measured value.  
Percent: If HDL is 20% of the total cholesterol, the risk of heart disease is average. If HDL is more than 20% of the total cholesterol, the risk of heart disease is less than average. This is usually expressed as a ratio of cholesterol to HDL. It is desirable for the cholesterol/HDL ratio to be less than 5.
http://www.labtestsonline.org.uk/understanding/analytes/hdl/test.html#what

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