Sunday, 19 December 2010

crabsallover PSA test for Prostate cancer

crabsallover tested Twin Oaks - Nigel Savage, blood tested: 15-Jul 2010, report no: 52588-280541315
test: 0.7 ug/L = 0.7ng/ml = normal


Levels under 4 ng/mL are usually considered “normal.”
Levels over 10 ng/mL are usually considered “high”
Levels between 4 and 10 ng/mL are usually considered “intermediate.”

The 'normal' value for total PSA varies with age and is generally considered to be under 3.0 nanograms (ng) per millilitre (mL) in men under 60 years of age of blood, under 4.0 ng per mL in men 60 - 69 years of age, and under 5.0 ng per mL in men over 70 years of age. Total PSA levels greater than 10.0 ng/mL may indicate a high probability of prostate cancer. Increased levels of PSA in those with a small prostate gland volume (which can be measured using ultrasound at the time of biopsy) indicate a higher probability of cancer. Levels between 4.0 ng/mL and 10.0 ng/mL may be due to BPH, a non-cancerous swelling of the prostate which occurs most frequently in elderly men. Increased total PSA levels may also indicate a condition called prostatitis, which is caused by an infection.

There is some evidence that the free PSA ratio (the percent of total PSA not bound to proteins) can help predict the probability of cancer, especially in patients with total PSA levels in the 'grey-area’ range of 4.0 to 10.0 ng/mL. This test may also be useful in early diagnosis of disease when values are between 2.5 and 4.0. A free-PSA test result above 25% is thought to suggest a lower risk of cancer, whereas a lower percentage suggests a higher probability of disease. This ratio may help reduce the number of unnecessary biopsies. A recent study also suggests that very low ratios of free PSA to total PSA (less than 14%) might be seen with a more aggressive form of the disease. Further studies are now being undertaken.

In most cases, test results are reported as numbers rather than as "high" or "low", "positive" or "negative", or "normal". In order for the doctor to properly understand laboratory results it is necessary for them to know what the reference range (or ‘normal value’ range) is for the laboratory where the test is performed. However, reference ranges can be influenced by the patient's age and sex and, amongst other things, by what drugs they are receiving, the time of day and what they have eaten. Reference ranges can also influenced by the test method and instrument used by laboratory. To learn more about reference ranges, please read the article, Reference Ranges and What They Mean. 

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